Characterization of human myeloid cells in HIS and HIS-HUHEP mice.

<p>Representative FACS contour plots of liver-isolated cells from HIS-HUHEP mice are shown for each cell subset with the parental gating strategy indicated above the plot. Total numbers of human (A) monocytes (hCD45⁺ CD3^- CD14⁺), (B) myeloid dendritic cells (hCD45⁺ CD3^- CD14^- CD11c⁺ HLA-DR⁺), and (C) plasmacytoid dendritic cells (hCD45⁺ CD3^- CD14^- CD123⁺ HLA-DR⁺) were determined in the liver and spleen of HIS and HIS-HUHEP mice. * p< 0,05 unpaired two-tailed t test.