<p>Urine and renal tissue MDA levels were markedly elevated in mice with anti-GBM glomerulonephritis compared with the normal controls. Treatment with EGCG normalized the urine and renal tissue MDA levels. Serum MDA levels were not significantly altered among the three groups. Renal tissue GSH levels were modestly reduced in mice with anti-GBM glomerulonephritis compared with the normal controls. Treatment with EGCG increased the renal tissue GSH to supranormal levels. Values are expressed as mean ± SEM; n = 7–9 in each group.</p
<p>Kidneys from mice 4 weeks after induction of anti-GBM-GN with or without EGCG treatment and kidne...
<p>Western blot showed significant increase in the levels of p-Akt, p-JNK, p-ERK, and p-P38 in vehic...
Background. From a diagnostic point of view it would be important to learn more about the relationsh...
<p>Following the challenge with anti-GBM serum, 129×1/SvJ mice (<i>n</i> = 3–9 per group) showed inc...
<p>At the end of the 3-week observation period, the vehicle-treated mice with anti-GBM-GN developed ...
<p>Kidneys from mice 4 weeks after induction of anti-GBM-GN with or without EGCG treatment and kidne...
<p><i>129/svj</i> mice were challenged with anti-GBM antibody on day 0 and then treated with hKLK1-M...
<p>Reduced glutathione (GSH), oxidized glutathione (GSSG) and malondialdehyde (MDA) were measured in...
<p>BALB/c mice were administrated intramuscularly with 100 µg/mouse pGRN or pcDNA3.1 to overexpress ...
The relationship between methylglyoxal (MGO) and D-lactate during saikosaponin C (SSC) treatment of ...
<p>HPLC analyses of renal GSH (A) or cysteine (Cys) (B) were carried out on 3-mm slices of kidneys f...
<p>(<i>a</i>) Increased Scr after anti-GBM serum challenge. On D12, each nephritis group showed sign...
<p>(A) Compared to normal control (NC) mice given vehicle (red unfilled squares) or BR-4628 (blue un...
<p>Western blot showed significant reduction in the levels of Nrf2, GCLc, GCLm, and GPx1 in vehicle-...
<p>Results are expressed as the means ± SD (n = 5). Significant differences from the control (CK) gr...
<p>Kidneys from mice 4 weeks after induction of anti-GBM-GN with or without EGCG treatment and kidne...
<p>Western blot showed significant increase in the levels of p-Akt, p-JNK, p-ERK, and p-P38 in vehic...
Background. From a diagnostic point of view it would be important to learn more about the relationsh...
<p>Following the challenge with anti-GBM serum, 129×1/SvJ mice (<i>n</i> = 3–9 per group) showed inc...
<p>At the end of the 3-week observation period, the vehicle-treated mice with anti-GBM-GN developed ...
<p>Kidneys from mice 4 weeks after induction of anti-GBM-GN with or without EGCG treatment and kidne...
<p><i>129/svj</i> mice were challenged with anti-GBM antibody on day 0 and then treated with hKLK1-M...
<p>Reduced glutathione (GSH), oxidized glutathione (GSSG) and malondialdehyde (MDA) were measured in...
<p>BALB/c mice were administrated intramuscularly with 100 µg/mouse pGRN or pcDNA3.1 to overexpress ...
The relationship between methylglyoxal (MGO) and D-lactate during saikosaponin C (SSC) treatment of ...
<p>HPLC analyses of renal GSH (A) or cysteine (Cys) (B) were carried out on 3-mm slices of kidneys f...
<p>(<i>a</i>) Increased Scr after anti-GBM serum challenge. On D12, each nephritis group showed sign...
<p>(A) Compared to normal control (NC) mice given vehicle (red unfilled squares) or BR-4628 (blue un...
<p>Western blot showed significant reduction in the levels of Nrf2, GCLc, GCLm, and GPx1 in vehicle-...
<p>Results are expressed as the means ± SD (n = 5). Significant differences from the control (CK) gr...
<p>Kidneys from mice 4 weeks after induction of anti-GBM-GN with or without EGCG treatment and kidne...
<p>Western blot showed significant increase in the levels of p-Akt, p-JNK, p-ERK, and p-P38 in vehic...
Background. From a diagnostic point of view it would be important to learn more about the relationsh...