<p>At the end of the 3-week observation period, the vehicle-treated mice with anti-GBM-GN developed renal insufficiency and proteinuria in contrast to the normal control group. The EGCG-treated mice showed significantly less proteinuria and lower serum creatinine than the vehicle-treated mice. Values are expressed as mean ± SEM; n = 7–9 in each group. </p
<p>The graphs summarize results of serum creatinine and albumin:creatinine ratio in the urine of con...
To elucidate the physiologic function of renal globotriaosylceramide (Gb3/CD77), which up-to-date ha...
<p>Panel A. Histological examination revealed significant protein nitration in the renal tubules of ...
<p>Kidneys from mice 4 weeks after induction of anti-GBM-GN with or without EGCG treatment and kidne...
<p>Cisplatin caused significant renal dysfunction as measured by the levels of creatinine (Panel A) ...
<p>Western blot showed significant increase in the levels of p-Akt, p-JNK, p-ERK, and p-P38 in vehic...
<p>Urine and renal tissue MDA levels were markedly elevated in mice with anti-GBM glomerulonephritis...
<p>(A) Compared to normal control (NC) mice given vehicle (red unfilled squares) or BR-4628 (blue un...
<p>Following the challenge with anti-GBM serum, 129×1/SvJ mice (<i>n</i> = 3–9 per group) showed inc...
<p>Western blot showed significant reduction in the levels of Nrf2, GCLc, GCLm, and GPx1 in vehicle-...
<p>Kidneys from mice 4 weeks after induction of anti-GBM-GN with or without EGCG treatment and kidne...
<p><i>129/svj</i> mice were challenged with anti-GBM antibody on day 0 and then treated with hKLK1-M...
<p>Histological staining with PAS and hematoxylin shows the kidney structure of (A) a normal mouse. ...
<p>Cisplatin administration resulted in severe tubular damage as shown by histological examination u...
<p>(<i>a</i>) Increased Scr after anti-GBM serum challenge. On D12, each nephritis group showed sign...
<p>The graphs summarize results of serum creatinine and albumin:creatinine ratio in the urine of con...
To elucidate the physiologic function of renal globotriaosylceramide (Gb3/CD77), which up-to-date ha...
<p>Panel A. Histological examination revealed significant protein nitration in the renal tubules of ...
<p>Kidneys from mice 4 weeks after induction of anti-GBM-GN with or without EGCG treatment and kidne...
<p>Cisplatin caused significant renal dysfunction as measured by the levels of creatinine (Panel A) ...
<p>Western blot showed significant increase in the levels of p-Akt, p-JNK, p-ERK, and p-P38 in vehic...
<p>Urine and renal tissue MDA levels were markedly elevated in mice with anti-GBM glomerulonephritis...
<p>(A) Compared to normal control (NC) mice given vehicle (red unfilled squares) or BR-4628 (blue un...
<p>Following the challenge with anti-GBM serum, 129×1/SvJ mice (<i>n</i> = 3–9 per group) showed inc...
<p>Western blot showed significant reduction in the levels of Nrf2, GCLc, GCLm, and GPx1 in vehicle-...
<p>Kidneys from mice 4 weeks after induction of anti-GBM-GN with or without EGCG treatment and kidne...
<p><i>129/svj</i> mice were challenged with anti-GBM antibody on day 0 and then treated with hKLK1-M...
<p>Histological staining with PAS and hematoxylin shows the kidney structure of (A) a normal mouse. ...
<p>Cisplatin administration resulted in severe tubular damage as shown by histological examination u...
<p>(<i>a</i>) Increased Scr after anti-GBM serum challenge. On D12, each nephritis group showed sign...
<p>The graphs summarize results of serum creatinine and albumin:creatinine ratio in the urine of con...
To elucidate the physiologic function of renal globotriaosylceramide (Gb3/CD77), which up-to-date ha...
<p>Panel A. Histological examination revealed significant protein nitration in the renal tubules of ...