<p>(A) Representative images of γH2AX foci in untreated cells, and in cells irradiated with 2 Gy 1h, 7h and 24h post-IR. Rad51 foci in cells at 24h post-IR are also shown. (B) Percentage of cells with γH2AX foci at the indicated times post-IR. (C) and (D) Quantification of the number of γH2AX foci per cell at 7 and 24h post-IR. In all quantifications data represent the mean values of at least 2 independent experiments. (** p<0.01, * p<0.05, compared to LINF cells). A minimum of 100 cells per experiment and cell line were counted.</p
<p><b>A</b>, Flowchart showing experimental procedure. <b>B</b>, Representative images for different...
<p>Kinetics of γ-H2AX foci removal after irradiation. Non-stem and CSC-like MDA-MB-435 and MDA-MB-23...
When early radiation damage to biological systems is studied based on the formation of foci at the l...
<p>(A) Asynchronous cells were treated with 2 Gy IR, fixed at the indicated times post-irradiation, ...
<p>(A) HCT116<sup><i>PARP1</i>-/-</sup> cells (clones C2 and C4) and control PARP1-proficient HCT116...
<p>HEK293 cells transfected with si-ctrl or si-RAD18 were exposed to 2 Gy IR, labeled with EdU, and ...
<p>(<b>A</b>) <i>Left panel</i>, Incidence of γ-H2AX foci in human and macaque blood samples irradia...
(A) Representative immunofluorescence images of 387 GSCs harvested at 30 min, 24 hrs and 48 hours af...
<p>(A) Values of γ-H2AX foci FI are mean ± S.D. from SOID determinations carried out in at least fou...
(A) Analysis of RAD51 distribution by recovery time. Four substages were considered (MP: mid pachyte...
<p>(A) Gating on G1, S and G2/M cells. (B) γH2AX histograms of the gated G2/M phase population of no...
<p>(A) γ-H2AX foci distribution at 24 hours after exposure of 100% of the cells to 0.5 Gy or 10% of ...
<p>Irradiation took place on t = 0. Foci formation can be observed already a few seconds after irra...
<p>Kinetics of γ-H2AX foci removal after irradiation. Non-stem and CSC-like MDA-MB-435 and MDA-MB-23...
<p><i>A</i>) γ-H2AX foci staining. D54 cells were mock treated or irradiated at 5 Gy, and γ-H2AX foc...
<p><b>A</b>, Flowchart showing experimental procedure. <b>B</b>, Representative images for different...
<p>Kinetics of γ-H2AX foci removal after irradiation. Non-stem and CSC-like MDA-MB-435 and MDA-MB-23...
When early radiation damage to biological systems is studied based on the formation of foci at the l...
<p>(A) Asynchronous cells were treated with 2 Gy IR, fixed at the indicated times post-irradiation, ...
<p>(A) HCT116<sup><i>PARP1</i>-/-</sup> cells (clones C2 and C4) and control PARP1-proficient HCT116...
<p>HEK293 cells transfected with si-ctrl or si-RAD18 were exposed to 2 Gy IR, labeled with EdU, and ...
<p>(<b>A</b>) <i>Left panel</i>, Incidence of γ-H2AX foci in human and macaque blood samples irradia...
(A) Representative immunofluorescence images of 387 GSCs harvested at 30 min, 24 hrs and 48 hours af...
<p>(A) Values of γ-H2AX foci FI are mean ± S.D. from SOID determinations carried out in at least fou...
(A) Analysis of RAD51 distribution by recovery time. Four substages were considered (MP: mid pachyte...
<p>(A) Gating on G1, S and G2/M cells. (B) γH2AX histograms of the gated G2/M phase population of no...
<p>(A) γ-H2AX foci distribution at 24 hours after exposure of 100% of the cells to 0.5 Gy or 10% of ...
<p>Irradiation took place on t = 0. Foci formation can be observed already a few seconds after irra...
<p>Kinetics of γ-H2AX foci removal after irradiation. Non-stem and CSC-like MDA-MB-435 and MDA-MB-23...
<p><i>A</i>) γ-H2AX foci staining. D54 cells were mock treated or irradiated at 5 Gy, and γ-H2AX foc...
<p><b>A</b>, Flowchart showing experimental procedure. <b>B</b>, Representative images for different...
<p>Kinetics of γ-H2AX foci removal after irradiation. Non-stem and CSC-like MDA-MB-435 and MDA-MB-23...
When early radiation damage to biological systems is studied based on the formation of foci at the l...