Segmentation of the regions of interest (ROI) CE-T1 tumor and T2 peritumoral edema.

<p>Glioblastoma of the left temporal lobe in patient 6. Coregistered images from the different sequences showing an exemplary slice of the whole tumor volume for this patient. <b>A)</b> CE-T1 tumor ROI (red line) segmented on CE T1-weighted image while thoroughly excluding central necrosis. <b>B)</b> T2 peritumoral edema ROI (green line) segmented on T2-weighted image. <b>C)</b> Coregistered ADC map and <b>D)</b> MTR_asym contrast illustrating both ROIs. The glioblastoma tumor and the cerebrospinal fluid in sulci and ventricles display hyperintense on NOE mediated CEST based on MTR_asym.