Effect of GNPs on intracellular ROS levels in GCLC siRNA pretreated cells.

<p>Exponentially growing cells were transfected with negative control and GCLC siRNA-1 for 24 hours, following treated with GNPs (20μM), GNPs (20μM) and GSH (1mM), GNPs (20μM) and NAC (1mM). ROS levels were measured. Graphs indicate ROS (as determined by DCF) levels (%) compared with negative control cells. Each bar represents the mean (±SD n = 4) of triplicate determinations. **p<0.01