<p>Mice were transplanted with a minimal human islet graft (250 islets) and treated with or without a low (20μg/kg/day) or high (200μg/kg/day) dose of exendin-4 for 15 days while monitoring glycemic levels and body weight for saline treated controls (black line), and exendin-4 treated groups (20μg/kg/day (orange line) and 200μg/kg/day (green line)). (a) Random blood glucose levels over the first 12 days of treatment (b) with corresponding AUC representing the different groups. (c) Body weight during the first 12 days of treatment (d) with corresponding AUC calculated for each group. **p<0.01 by one-way ANOVA followed by Bonferroni correction vs. corresponding saline treated control, and values are expressed as mean ±SD.</p
Exendin-4 (Ex-4) is a Glucagon-like peptide 1 (GLP-1) receptor agonist approved for the treatment of...
Exendin-4 (Ex-4) is a Glucagon-like peptide 1 (GLP-1) receptor agonist approved for the treatment of...
The aim of this study was to evaluate Exendin-4 (EX-4) effects on islet volume and number in the mou...
<p>Mice transplanted with a minimal human islet graft (250 islets) were treated with or without exen...
<p>Circulating levels of fasting blood glucose (a) and C-peptide (b) after 15 days of treatment -/+ ...
Islet transplantation has become a viable clinical treatment, but is still compromised by long-term ...
Islet transplantation has become a viable clinical treatment, but is still compromised by long-term ...
<p>Blood sampling was performed on day 7 and 15 of treatment -/+ exendin-4 with a low (20μg/kg/day) ...
<p>After 15 days of treatment -/+ exendin-4 treatment with a low (20μg/kg/day) or high (200μg/kg/day...
Aims: Type 2 diabetes is highly prevalent in the elderly population. Glucagon like Peptide-1 mimetic...
Exendin-4 reduces fasting and postprandial glucose and de-creases energy intake in healthy volunteer...
OBJECTIVE—The aim of this study was to find an effective treatment for the genetic form of diabetes ...
Transplantation of pancreatic islets into the liver via the portal vein has emerged as a treatment ...
<p>In the double islet transplantation model, the first mouse islet graft is used to achieve normogl...
Islet transplantation has become a viable clinical treatment, but is still compromised by long-term ...
Exendin-4 (Ex-4) is a Glucagon-like peptide 1 (GLP-1) receptor agonist approved for the treatment of...
Exendin-4 (Ex-4) is a Glucagon-like peptide 1 (GLP-1) receptor agonist approved for the treatment of...
The aim of this study was to evaluate Exendin-4 (EX-4) effects on islet volume and number in the mou...
<p>Mice transplanted with a minimal human islet graft (250 islets) were treated with or without exen...
<p>Circulating levels of fasting blood glucose (a) and C-peptide (b) after 15 days of treatment -/+ ...
Islet transplantation has become a viable clinical treatment, but is still compromised by long-term ...
Islet transplantation has become a viable clinical treatment, but is still compromised by long-term ...
<p>Blood sampling was performed on day 7 and 15 of treatment -/+ exendin-4 with a low (20μg/kg/day) ...
<p>After 15 days of treatment -/+ exendin-4 treatment with a low (20μg/kg/day) or high (200μg/kg/day...
Aims: Type 2 diabetes is highly prevalent in the elderly population. Glucagon like Peptide-1 mimetic...
Exendin-4 reduces fasting and postprandial glucose and de-creases energy intake in healthy volunteer...
OBJECTIVE—The aim of this study was to find an effective treatment for the genetic form of diabetes ...
Transplantation of pancreatic islets into the liver via the portal vein has emerged as a treatment ...
<p>In the double islet transplantation model, the first mouse islet graft is used to achieve normogl...
Islet transplantation has become a viable clinical treatment, but is still compromised by long-term ...
Exendin-4 (Ex-4) is a Glucagon-like peptide 1 (GLP-1) receptor agonist approved for the treatment of...
Exendin-4 (Ex-4) is a Glucagon-like peptide 1 (GLP-1) receptor agonist approved for the treatment of...
The aim of this study was to evaluate Exendin-4 (EX-4) effects on islet volume and number in the mou...