Effect of CO on the expression of NLRP3, ASC, and caspase-1 in mesenteric lymph nodes (A) and in ileum mucosa (B) of endotoxin-injected mice.

<p>Mice received by gavage 6.5 mg/kg CO (endotoxin-COL), 13 mg/kg CO (endotoxin-COM), 26 mg/kg CO (endotoxin-COH), or the vehicle (endotoxin-V) every other day 8 times followed by injection with endotoxin from <i>S</i>. <i>typhimurium</i> (i.p., 10 mg/kg body weight). Control mice were pretreated with vehicle (control-V) followed by injection with saline. Samples were collected at 12 h after injection. Data are means ± SDs for three mice in each group. #Significantly different from the control (p < 0.05). a, b, and c not sharing the same letter are significantly different (p < 0.05).