<p>(A): The mice tumors’ volume in different groups. After six weeks of treatment, digoxin therapy decreased the tumors’ volume, which was significantly smaller than those in the saline control group (p<0.05). (B): IHC results in different groups. Additionally, the IHC results confirmed the effect of digoxin: Digoxin therapy decreased the HIF-lα and SCF positive tumor cells compared to the saline control group, respectively.</p
International audienceCellular metabolic alterations are now well described as implicated in cancer ...
<p><b>A</b>) Photomicrographs for colon tissues immunohistochemically stained for CD<sub>34</sub> (s...
An evolving field of anti-tumor therapy is the use of drugs that alter the expression of important r...
<p>(a) A549 cell viability was measured using the Prestoblue Cell Viability Reagent at different tim...
<p><b>A</b>. 1 x 10<sup>5</sup> human A549, A549/dx, HT29, HT29/dx cells were implanted subcutaneous...
Non-small cell lung cancer is the predominant type of lung cancer, resulting in high mortality world...
<p>In digoxin-treated cells, the phosphorylation of Src and its related proteins was inhibited, whic...
PURPOSE: Non-medullary thyroid cancer (NMTC) treatment is based on the ability of thyroid follicular...
<p>Western blotting analyses of phosphorylated and non-phosphorylated PI3K, AKT, MEK1/2, ERK, FAK, S...
<p>(a) A549 cells were pretreated with or without MG132 (10 μM) for 2 h, then treated with digoxin (...
Non-small cell lung cancer is the predominant type of lung cancer, resulting in high mortality world...
Clinical and experimental evidence supports a role for cardiac glycosides (CGs) as potential novel a...
<p>HeLa (A) or RKO (B) cells were treated with digoxin (green symbols) or 21-BD (red symbols) for 24...
<p>(A) Cal-27 cells were used to establish xenograft tumors in BALB/c mice, and animals were treated...
<p>(A, B): Subcutaneous tumors were established in mice inoculated with HepG2 cells. Animals were gi...
International audienceCellular metabolic alterations are now well described as implicated in cancer ...
<p><b>A</b>) Photomicrographs for colon tissues immunohistochemically stained for CD<sub>34</sub> (s...
An evolving field of anti-tumor therapy is the use of drugs that alter the expression of important r...
<p>(a) A549 cell viability was measured using the Prestoblue Cell Viability Reagent at different tim...
<p><b>A</b>. 1 x 10<sup>5</sup> human A549, A549/dx, HT29, HT29/dx cells were implanted subcutaneous...
Non-small cell lung cancer is the predominant type of lung cancer, resulting in high mortality world...
<p>In digoxin-treated cells, the phosphorylation of Src and its related proteins was inhibited, whic...
PURPOSE: Non-medullary thyroid cancer (NMTC) treatment is based on the ability of thyroid follicular...
<p>Western blotting analyses of phosphorylated and non-phosphorylated PI3K, AKT, MEK1/2, ERK, FAK, S...
<p>(a) A549 cells were pretreated with or without MG132 (10 μM) for 2 h, then treated with digoxin (...
Non-small cell lung cancer is the predominant type of lung cancer, resulting in high mortality world...
Clinical and experimental evidence supports a role for cardiac glycosides (CGs) as potential novel a...
<p>HeLa (A) or RKO (B) cells were treated with digoxin (green symbols) or 21-BD (red symbols) for 24...
<p>(A) Cal-27 cells were used to establish xenograft tumors in BALB/c mice, and animals were treated...
<p>(A, B): Subcutaneous tumors were established in mice inoculated with HepG2 cells. Animals were gi...
International audienceCellular metabolic alterations are now well described as implicated in cancer ...
<p><b>A</b>) Photomicrographs for colon tissues immunohistochemically stained for CD<sub>34</sub> (s...
An evolving field of anti-tumor therapy is the use of drugs that alter the expression of important r...