Influence of SCF on the biological behavior of PDAC cell.

<p>(A) and (B): Colony formation results showed the SCF effect on cell proliferation. After applying the interference of exogenous SCF or anti-SCF antibody in PANC-1 cells, the proliferative ability in the interference groups significantly increased or decreased compared with those of the control groups (p<0.05, respectively). * stands for p<0.05 (mark group VS control group). (C): The scratch results showed the SCF effect on cell invasion. After the interference of exogenous SCF and anti-SCF antibody, the widths in the SCF or anti-SCF groups were smaller or bigger than those in the NC or HC control group (p < 0.05, respectively). (D): The transwell chambers results showed the SCF effect on cell invasion. After the interference of exogenous SCF or anti-SCF, the cell number through the membrane was significantly more or less than the control group (p < 0.05, respectively). * stands for p<0.05 (N+SCF group VS NC group), and # stands for p<0.05 (H +anti-SCF group VS HC group).