Chromatin changes at subtelomeres in <i>fft3Δ</i> cells coincide with changes in nuclear organization.

<p><b>(A)</b> Association with the nuclear envelope in wild type is lost in <i>fft3Δ</i> cells. Shown over the left subtelomere of chromosome II are log2-ratios of Pol II enrichment in <i>fft3Δ vs</i>. wt, log2-enrichment of Fft3-myc ChIP over anti-myc control ChIP, log2-enrichment Man1-Dam over the Dam only control in wild type, log2-enrichment Man1-Dam over Dam only control in <i>fft3Δ</i> cells. <b>(B)</b> Subtelomeric chromatin is associated with the nuclear periphery in wild type cells. Man1-Dam enrichment over Dam-only control is shown as boxplot. <b>(C)</b> Association of the subtelomeres with the nuclear periphery is lost in <i>fft3Δ</i> cells. Man1-Dam enrichment over Dam-only control is shown as boxplot. <b>(D)</b> Fft3 is not enriched at subtelomeres. Fft3-enrichment over anti-myc control is shown as boxplot.