S100A6 promotes PDAC cell migration and invasion in vitro.

<p>(A) The wound-healing assay, cells overexpressing S100A6 (left), control cells (right). (B) The wound-healing rate was significantly higher in S100A6 overexpressing cells, relative to control cells, at 24 and 48 h. (C) Transwell assay, “I” represents S100A6 overexpression in the migration assay; “II” represents the control group in the migration assay; “III” represents S100A6 overexpression in the invasion assay; “IV” represents the control group in the invasion assay. (D) Representative statistical chart for the transwell assay, showing a significant increase in migration (I) and invasion (II) by S100A6 overexpressing cells, relative to control cells. *p < 0.05; **p < 0.01.