S100A6 overexpression did not influence migration and invasion in β-catenin-knockdown stable cells.

<p>(A) The wound-healing assay revealed no change in the migration of β-catenin-shRNA cells overexpressing S100A6 (left) compared to the β-catenin-shRNA control group (right). (B) There was no significant difference in the wound-healing rate between the two groups. (C) There was no significant difference in the transwell assay results between the two groups, with respect to both migration and invasion (×40). “I” represents β-catenin-shRNA+S100A6 overexpression in the migration assay; “II” represents β-catenin-shRNA+S100A6-control in the migration assay; “III” represents β-catenin-shRNA+S100A6 overexpression in the invasion assay; “IV” represents β-catenin-shRNA+S100A6-control in the invasion assay. (D) Representative statistical chart for the transwell assay, showing no significant difference in the migration (I) or invasion (II) assays between the two groups.