Phenotypic characterization of the most common myeloid subsets.

<p>¹: This is a subset of CM1, CM2 and CM3 where DR has been lost. Often this designation is currently grouped independent of the designation of CD16. However, CM1, CM2 and CM3 have been shown to have unique positive effects on immunity. Thus, an alternative designation for the suppressive version of CM1, CM2 and CM3 is CM1-DRneg, etc.</p><p>²: Termed suppressive monocytes (Refs. [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0121546#pone.0121546.ref017" target="_blank">17</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0121546#pone.0121546.ref018" target="_blank">18</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0121546#pone.0121546.ref028" target="_blank">28</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0121546#pone.0121546.ref029" target="_blank">29</a>]).</p><p>³: MDSC were only classified as MO-MDSC and GR-MDSC without clear designation of what these cells and/or subsets are⁸.</p><p>⁴: GR-MDSCs generally have the same surface markers as granulocytes but are identified by altered density properties in density gradient purifications of mononuclear cells.</p><p>Phenotypic characterization of the most common myeloid subsets.