Expression of mRNA and proteins involved in autophagy regulation and induction in muscle of sedentary and exercise-trained normotensive and hypertensive rats.

<p><i>A</i>: quantitative analysis of Beclin-1 mRNA in WG and LV. <i>B</i>: representative immunoblots and quantitative analysis of Beclin-1, BNIP3, and Bcl-xL protein in WG and LV. <i>C</i>: representative immunoblots and quantitative analysis of Bcl-2 and p-Bcl-2 (Ser⁸⁷) protein in WG and LV (calculated p-Bcl-2:Bcl-2 ratio is also shown). Portions of Ponceau stained membranes are also shown to verify equal loading and quality of transfer. Values are means ± SEM (<i>n</i> = 9–12). ^‡ p<0.005 vs WKY (main effect); ^§ p<0.001 vs WKY (main effect); * p<0.05 vs SED (main effect); ^† p<0.01 vs SED (main effect).