Hypoxia upregulates trophoblast miR-517a/b and miR-517c expression.

<p>miR-517a/b (<b>A</b>) and miR-517c (<b>B</b>) expression in EVT cells treated with the indicated doses (0–100 μM) of CoCl₂ for 6hrs. Time course of HIF1α protein (C) expression in EVTs treated with CoCl₂ (100 μM). (D) Invasion assay of EVTs treated with 100 μM CoCl₂. Values are mean ± SEM. n = 4 (A and B), n = 3 (D) *p<0.05, **p < 0.01.