<p><b>A, B.</b> U373 cells were inoculated into the brain of nude mice in the absence or in the presence of botulinum toxin C1 (BoNT/C1), which specifically cleaves the SNARE proteins Stx1a/b and SNAP25. <b>(A)</b> Growth curve of GBM tumors determined by luciferase quantification (* p ≤ 0.05 at 40 DPI), and <b>(B)</b> scatter plot showing the individual size of the U373 GBM tumors formed after 40 DPI, demonstrating a marked reduction of GBM after BoNT/C1 treatment.</p
AbstractBotulinum neurotoxins (BoNTs), the causative agent of human botulism, are the most potent na...
SummaryGlioblastoma multiforme (GBM) is the most aggressive form of brain cancer with marginal life ...
AIM OF THE STUDY: Botulinum toxin A (BoNT/A) has been recently used in the treatment of benign prost...
Glioblastoma (GBM) is the most prevalent adult brain tumor, with virtually no cure, and with a media...
Glioblastoma (GBM) is the most prevalent adult brain tumor, with virtually no cure, and with a media...
<p>An equal number of the indicated U373 cell populations were stereotactically inoculated into the ...
Glioblastoma (GBM) is the most prevalent adult brain tumor, with virtually no cure, and with a media...
Glioblastoma (GBM) is the most prevalent adult brain tumor, with virtually no cure, and with a media...
Background: Glioblastoma multiforme (GBM) is the most type of brain malignancy in adults. Radical ex...
Tumor innervation has been shown to be utilized by some solid cancers to support tumor initiation, g...
Precise cellular targeting of macromolecular cargos has important biotechnological and medical impli...
PURPOSE: Structural and functional abnormalities in the tumor vascular network are considered factor...
Botulinum neurotoxins produced by Clostridium botulinum cause flaccid paralysis by inhib-iting neuro...
<div><p>Botulinum neurotoxin serotype A (BoNT/A), a potent therapeutic used to treat various disorde...
Neuroblastomas constitute a major cause of cancer-related deaths in young children. In recent years,...
AbstractBotulinum neurotoxins (BoNTs), the causative agent of human botulism, are the most potent na...
SummaryGlioblastoma multiforme (GBM) is the most aggressive form of brain cancer with marginal life ...
AIM OF THE STUDY: Botulinum toxin A (BoNT/A) has been recently used in the treatment of benign prost...
Glioblastoma (GBM) is the most prevalent adult brain tumor, with virtually no cure, and with a media...
Glioblastoma (GBM) is the most prevalent adult brain tumor, with virtually no cure, and with a media...
<p>An equal number of the indicated U373 cell populations were stereotactically inoculated into the ...
Glioblastoma (GBM) is the most prevalent adult brain tumor, with virtually no cure, and with a media...
Glioblastoma (GBM) is the most prevalent adult brain tumor, with virtually no cure, and with a media...
Background: Glioblastoma multiforme (GBM) is the most type of brain malignancy in adults. Radical ex...
Tumor innervation has been shown to be utilized by some solid cancers to support tumor initiation, g...
Precise cellular targeting of macromolecular cargos has important biotechnological and medical impli...
PURPOSE: Structural and functional abnormalities in the tumor vascular network are considered factor...
Botulinum neurotoxins produced by Clostridium botulinum cause flaccid paralysis by inhib-iting neuro...
<div><p>Botulinum neurotoxin serotype A (BoNT/A), a potent therapeutic used to treat various disorde...
Neuroblastomas constitute a major cause of cancer-related deaths in young children. In recent years,...
AbstractBotulinum neurotoxins (BoNTs), the causative agent of human botulism, are the most potent na...
SummaryGlioblastoma multiforme (GBM) is the most aggressive form of brain cancer with marginal life ...
AIM OF THE STUDY: Botulinum toxin A (BoNT/A) has been recently used in the treatment of benign prost...