Clinical evaluation.

<p><b>A: Pedigree of the five-generation Chinese family with autosomal dominant congenital cataract (ADCC).</b> Squares and circles indicate males and females, respectively. Filled symbols indicate affected members and empty symbols indicate unaffected individuals. The diagonal line indicates a deceased family member and the arrow indicates the proband. Family members whose DNA was analyzed by sequencing and restriction enzyme digestion are indicated by asterisks. <b>B: Photograph of the right eye of the proband.</b> The photograph (diffuse illumination) of the proband (V: 1) before surgery shows a posterior polar cataract with cotton-like opacities in the posterior subcapsular cortex. The same phenotype was noted bilaterally.