AFM characterisation of wt β2m and DE loop mutants aggregates incubated for one week.

<p>Tapping mode AFM images (height data) of mature fibrils of wt β2m and DE loop mutants obtained after one week incubation. Scan size 1.2 μm; the scale bars correspond to a Z range of: A and D) 55 nm; B) 70 nm; C) 65 nm. E-H) histograms of fibril height measured from fibril cross-sectional profiles in the topographic AFM images.