Inhibition of VRC01, 10–1074, b12 and PGT121 neutralizing activity in the TZM-bl assay against HIV RHPA4259.7 and SHIV-BaL-P4 by different macaque anti-idiotypic antibodies.

<p>Concentrations of each of the bnAb that inhibited the target virus at 50–80% was pre-incubated with or without serial dilutions of 7 different monkey plasma samples (color coded) prior to adding virus. Deviations from this “no serum” control line indicates interference from the macaque sample with neutralization of the bnAb.