<p>Effects of the superoxide anion scavenger, SOD (150 U/ml), on the concentration-response curves of phenylephrine in endothelium-intact aortic segments from both untreated and lead-treated rats. The graph demonstrates differences in the areas under the concentration-response curves (dAUC) between the groups. Densitometry of SOD Western blots in aortas from untreated and lead-treated rats (B). Representative blots are also shown. Each point represents the mean ± SEM. *p <0.05 versus the corresponding control by Student’s t-test. The number of animals used is indicated in parentheses.</p
<p>Quantification of the amplitude of O<sub>2</sub><sup>–</sup>CMH signal (A) and immunohistochemica...
<p>Effects of the nonselective K<sup>+</sup> channel blocker, TEA (2 mM) on the concentration-respon...
<p>Effect of L-NAME (LN, 100 μM) or superoxide dismutase (SOD, 150 U/mL) on the concentration-respon...
<p>Effects of the inhibitor Cu/Zn superoxide dismutase, DETCA (0.5 mM), on the concentration-respons...
<p>Effects of the hydrogen peroxide scavenger, catalase (1000 U/ml), on the concentration-response c...
<p>Densitometric analysis of the western blot to measure the superoxide dismutase Cu/Zn (Cu/ZnSOD) p...
<p>The inset shows differences in area under the concentration-response curves (dAUC) in endothelium...
<p>Densitometry analyses of the western blots for receptors AT<sub>1</sub> (E) and AT<sub>2</sub> (F...
<p>Effects of L-NAME (100 mM) treatment on phenylephrine-induced vasoconstriction in aortic rings fr...
<p>E-: endothelium-denuded, E+: intact segments. Differences in the area under the concentration-res...
<p>Effects of the specific NAD(P)H oxidase inhibitor, apocynin (0.3 mM), on the concentration-respon...
<p>Results (mean ± SEM) are expressed as SOD units /ml mg protein. Number of animals is indicated in...
<p>Effects of 30 days of exposure to lead acetate on the concentration-response curves of (A) phenyl...
<p>Differences in the area under the concentration-response curve (dAUC) in the aortic rings of cont...
<p>The results are expressed as the mean ± SEM; Emax, maximal effect expressed as a percentage of th...
<p>Quantification of the amplitude of O<sub>2</sub><sup>–</sup>CMH signal (A) and immunohistochemica...
<p>Effects of the nonselective K<sup>+</sup> channel blocker, TEA (2 mM) on the concentration-respon...
<p>Effect of L-NAME (LN, 100 μM) or superoxide dismutase (SOD, 150 U/mL) on the concentration-respon...
<p>Effects of the inhibitor Cu/Zn superoxide dismutase, DETCA (0.5 mM), on the concentration-respons...
<p>Effects of the hydrogen peroxide scavenger, catalase (1000 U/ml), on the concentration-response c...
<p>Densitometric analysis of the western blot to measure the superoxide dismutase Cu/Zn (Cu/ZnSOD) p...
<p>The inset shows differences in area under the concentration-response curves (dAUC) in endothelium...
<p>Densitometry analyses of the western blots for receptors AT<sub>1</sub> (E) and AT<sub>2</sub> (F...
<p>Effects of L-NAME (100 mM) treatment on phenylephrine-induced vasoconstriction in aortic rings fr...
<p>E-: endothelium-denuded, E+: intact segments. Differences in the area under the concentration-res...
<p>Effects of the specific NAD(P)H oxidase inhibitor, apocynin (0.3 mM), on the concentration-respon...
<p>Results (mean ± SEM) are expressed as SOD units /ml mg protein. Number of animals is indicated in...
<p>Effects of 30 days of exposure to lead acetate on the concentration-response curves of (A) phenyl...
<p>Differences in the area under the concentration-response curve (dAUC) in the aortic rings of cont...
<p>The results are expressed as the mean ± SEM; Emax, maximal effect expressed as a percentage of th...
<p>Quantification of the amplitude of O<sub>2</sub><sup>–</sup>CMH signal (A) and immunohistochemica...
<p>Effects of the nonselective K<sup>+</sup> channel blocker, TEA (2 mM) on the concentration-respon...
<p>Effect of L-NAME (LN, 100 μM) or superoxide dismutase (SOD, 150 U/mL) on the concentration-respon...