<p>A. Schematic of the targeting construct of Zip4 showing the region of the Zip4 gene flanked by the loxP sites. The cre recombinase induced recombination at these loxP sites which results in the excision of the portion of the Zip4 gene that contains 7 exons. B. PCR results obtained from ear skin samples.</p
Site-specific recombination systems are widespread and popular tools for all scientists interested i...
<p>A, breeding scheme: male wildtype mice with two <i>Pten</i> wildtype alleles (marked “+”) were br...
Site-specific recombinases (SSR) are utilized as important genome engineering tools to precisely mod...
<p>A. PCR results from skin, liver and islet DNA samples showing the wild type (WT), LoxP/LoxP and r...
<p>(<b>A</b>) The mouse <i>Zip5</i> gene was captured using gap-repair and manipulated using galK re...
<p>PCR of genomic DNA extracted from the tumor and the corresponding tail (control for lack of recom...
<p><b>(A)</b> Scheme of the wild-type allele, the targeting vector, and the targeted CAP2/<i>Tmprss4...
AbstractThe site-specific DNA recombinase Cre is being used to develop a new generation of tools for...
Gene targeting in ES cells is extensively used to generate designed mouse mutants and to study gene ...
<p>(A) Strategy for generation of <i>Cul4b</i> floxed targeting vector. On the top was shown the wil...
(A) Mouse breeding strategy. IL-4Rα−/− BALB/c mice were intercrossed for two generations with transg...
<p>(<b>A</b>) Schematic illustration of the targeting strategy. The <i>cpeb4</i> gene consists of 10...
Cre-mediated recombination leads to deletion of the stop cassette and expression of under transcrip...
Targeted gene mutation in the mouse is a primary strategy to understand gene function and relation t...
Gene targeting in ES cells is extensively used to generate designed mouse mutants and to study gene ...
Site-specific recombination systems are widespread and popular tools for all scientists interested i...
<p>A, breeding scheme: male wildtype mice with two <i>Pten</i> wildtype alleles (marked “+”) were br...
Site-specific recombinases (SSR) are utilized as important genome engineering tools to precisely mod...
<p>A. PCR results from skin, liver and islet DNA samples showing the wild type (WT), LoxP/LoxP and r...
<p>(<b>A</b>) The mouse <i>Zip5</i> gene was captured using gap-repair and manipulated using galK re...
<p>PCR of genomic DNA extracted from the tumor and the corresponding tail (control for lack of recom...
<p><b>(A)</b> Scheme of the wild-type allele, the targeting vector, and the targeted CAP2/<i>Tmprss4...
AbstractThe site-specific DNA recombinase Cre is being used to develop a new generation of tools for...
Gene targeting in ES cells is extensively used to generate designed mouse mutants and to study gene ...
<p>(A) Strategy for generation of <i>Cul4b</i> floxed targeting vector. On the top was shown the wil...
(A) Mouse breeding strategy. IL-4Rα−/− BALB/c mice were intercrossed for two generations with transg...
<p>(<b>A</b>) Schematic illustration of the targeting strategy. The <i>cpeb4</i> gene consists of 10...
Cre-mediated recombination leads to deletion of the stop cassette and expression of under transcrip...
Targeted gene mutation in the mouse is a primary strategy to understand gene function and relation t...
Gene targeting in ES cells is extensively used to generate designed mouse mutants and to study gene ...
Site-specific recombination systems are widespread and popular tools for all scientists interested i...
<p>A, breeding scheme: male wildtype mice with two <i>Pten</i> wildtype alleles (marked “+”) were br...
Site-specific recombinases (SSR) are utilized as important genome engineering tools to precisely mod...