ARG1 deletion prevents Ang II-induced vascular cell proliferation.

<p>PCNA was detected following treatments of Ang II (1mg/kg/day, 28 days) or saline (Sham) in WT and ARG1^+/− mice. Top, PCNA is stained red and cell nuclei are stained blue (DAPI) (20x magnification). Merged picture shows cells stained with PCNA antibody (red) and DAPI (blue). Bottom, Data presented quantitatively as percentage PCNA positive cells per total nuclei (DAPI stains) (mean+/-SEM, n = 5, 2 sections per mouse). *P< 0.05 vs. other groups. Size bars represent 50 μm.