The apoptosis of GCs in the MOB is elevated in AC3^−/− mice.

<p>(A) Representative images of active caspase-3 (green) and NeuN (red) staining in the GCL of AC3^−/− mice. Nuclei were counterstained with DAPI (blue). Scale bar, 100 μm. GCL, granule cell layer; ML, mitral cell layer. Dashed lines indicate GCL contour. The apoptotic GC indicated by arrowhead in (A) is shown at higher magnification in the vertical panels on right (scale bar, 5 μm). (B) Quantification of caspase-3⁺ cells in the GCL of AC3^+/+ and AC3^−/− mice. n = 5 per genotype. **<i>p</i> < 0.01, unpaired Student’s <i>t</i> test.