Effect of HIF-1α on the migration of NB cells.

<p>(A, D) The wound healing assay showed that HIF-1α overexpression did not increase migration in SH-SY5Y and IMR32 cells under normoxia (n = 9). (B, E) HIF-1α knockdown decreased migration in both cell lines under hypoxia (n = 9). (C, F) HIF-1α overexpression increased migration in both cell lines under hypoxia (n = 9). All ×40 magnification. Data are expressed as means ± SD.