Voiding behaviour of CYP-injected mice treated with saline or antidepressants.

<p>A, B, C: data describing the micturition pattern: first voiding latency (A), urine volume (B) and number of urine spots (C). Data are presented as mean+SEM. ANOVA and Duncan <i>post hoc</i> test (comparison with saline group) *: p<0.05, **: p<0.005, ***: p<0.001. D, E, F, G and H: representative UV images of urinary spots collected 48 hours after the beginning of the antidepressant treatment: control CYP-injected mouse (D), desipramine (E), imipramine (F) duloxetine (G) and 4-hydroxy-duloxetine-treated mouse (H). The images show a decrease in voiding behaviour in antidepressant-treated mice.