<p>Cells were treated for 24 h with various endogenous and synthetic steroids. Cells were lysed and luciferase activity was measured. Data are mean of triplicate measurements and are expressed as a fold induction over DMSO-treated cells. Similar data were obtained from three consecutive cell passages. Upper plots—androgens, middle plots—corticoids, lower plots—gestagens and estrogens.</p
Cancer cell heterogeneity is well-documented. Therefore, techniques to monitor single cell heterogen...
<p>Dose dependent changes in (A) calcium flux and (B) IP1 levels in cells upon stimulation with AR-<...
<p>(<b>A</b>) HEK293T cells were exposed to graded concentrations of wild type (WT) GnRH, R31C and e...
<p>Cells were treated for 24 h with various endogenous and synthetic steroids in the presence of tes...
<p>Cells were treated for 24 h with various endogenous and synthetic steroids in the presence of 5α-...
<p>Cells were treated for 24 h with 5α-dihydrotestosterone (DHT; 0.1 nM—10 μM), testosterone (10 nM)...
<p>Cells were treated with 5α-dihydrotestosterone (DHT; 100 nM) and vehicle (DMSO; 0.1% v/v) for tim...
<p><b>A–C,</b> YFP fluorescence intensities within the FP<sub>NLS</sub>FP-marked cell nuclei of each...
<p>Cells were treated for 24h with compounds A13 (A), H12 (B), or with classical drugs staurosporine...
<p>ARE reporter cells were exposed to (15 µM) for 24 h. The value for cells treated with vehicle DMS...
<p>MCF-7-MAR-ERE-Luc were treated with indicated compounds at 5 μM, 5 μM + 10 nM E2, or 2 μM + 10 nM...
<p>S2 cells transiently transfected with TRE-fluc, ARE-fluc or mRE-fluc plasmids, as indicated, were...
<p>FACS analysis of mCherry signals in (A) EP156T-AR-241B, (B) 957E/hTERT-AR-241B and (C) LNCaP-241B...
<p>(A) FACS analysis of mCherry signals in EPT3-PT1-AR-241B cells. Cells were grown in androgen free...
<p>ARE reporter cells were exposed to <b>33</b>, <b>34</b> and resveratrol (7.5 µM, 15 µM and 30 µM)...
Cancer cell heterogeneity is well-documented. Therefore, techniques to monitor single cell heterogen...
<p>Dose dependent changes in (A) calcium flux and (B) IP1 levels in cells upon stimulation with AR-<...
<p>(<b>A</b>) HEK293T cells were exposed to graded concentrations of wild type (WT) GnRH, R31C and e...
<p>Cells were treated for 24 h with various endogenous and synthetic steroids in the presence of tes...
<p>Cells were treated for 24 h with various endogenous and synthetic steroids in the presence of 5α-...
<p>Cells were treated for 24 h with 5α-dihydrotestosterone (DHT; 0.1 nM—10 μM), testosterone (10 nM)...
<p>Cells were treated with 5α-dihydrotestosterone (DHT; 100 nM) and vehicle (DMSO; 0.1% v/v) for tim...
<p><b>A–C,</b> YFP fluorescence intensities within the FP<sub>NLS</sub>FP-marked cell nuclei of each...
<p>Cells were treated for 24h with compounds A13 (A), H12 (B), or with classical drugs staurosporine...
<p>ARE reporter cells were exposed to (15 µM) for 24 h. The value for cells treated with vehicle DMS...
<p>MCF-7-MAR-ERE-Luc were treated with indicated compounds at 5 μM, 5 μM + 10 nM E2, or 2 μM + 10 nM...
<p>S2 cells transiently transfected with TRE-fluc, ARE-fluc or mRE-fluc plasmids, as indicated, were...
<p>FACS analysis of mCherry signals in (A) EP156T-AR-241B, (B) 957E/hTERT-AR-241B and (C) LNCaP-241B...
<p>(A) FACS analysis of mCherry signals in EPT3-PT1-AR-241B cells. Cells were grown in androgen free...
<p>ARE reporter cells were exposed to <b>33</b>, <b>34</b> and resveratrol (7.5 µM, 15 µM and 30 µM)...
Cancer cell heterogeneity is well-documented. Therefore, techniques to monitor single cell heterogen...
<p>Dose dependent changes in (A) calcium flux and (B) IP1 levels in cells upon stimulation with AR-<...
<p>(<b>A</b>) HEK293T cells were exposed to graded concentrations of wild type (WT) GnRH, R31C and e...