HIV-specific Tregs/Teffs ratio is affected by vaccination.

<p>(A) Gag p24-, LIPO-5- and CMV-Tregs responses prior and after vaccination (n = 14). (B) Pie chart showing LIPO-5-specific Tregs among LIPO-5-specific (CD134⁺CD25⁺) cells prior and after vaccination (n = 14). (C) Representative profiles after in vitro stimulation with LIPO-5 showing good and poor responder to vaccination (based on a viral load rebound). (D) Correlation between IFN-γ-producing and Tregs cells among LIPO-5-specific cells after in vitro stimulation. Data were analyzed by Wilcoxon matched-pairs signed rank test. *p < 0.05; **p < 0.01; ***p < 0.001. Spearman coefficient is indicated (r) as well as p value.