Effects of OCT4A and OCT4B on self-renewal in cervical cancer cell lines.

<p>(A), RT-PCR analysis of OCT4A and OCT4B expression in the indicated cell lines. Tera-1 cells as a positive control. (B), Identification of the stable transfected cells. GAPDH served as the loading control. (C) and (D), The number of tumorspheres/1,000 cells was counted from 5 consecutive passages. (E), Representative images of tumorspheres formed from the indicated cells. (F), The chemosensitivity of OCT4A- and OCT4B-overexpressing cells to cisplatin for 72 h.