<p>AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; NMDA, N-methyl-D-aspartic acid. Negative value of percent inhibition indicates stimulation of receptor activity.</p><p>Percent inhibition of receptors by TAK-063 at 10 μM.</p
<p>Inhibition [%] of complexes 1 and 2 [dose level of 25.0 μM] against human tumor cells.</p
Percent cell inhibition of DXH, EpiDXH and DNR against (a) H-1299 and (b) H-157 cell lines.</p
N-Methyl-D-aspartate (NMDA) receptor ligands regulate the bind-ing of uncompetitive antagonists in m...
<p>EGF, epidermal growth factor; HMG CoA, 3-hydroxy-3-methyl-glutaryl coenzyme A. Negative value of ...
<p>Inhibition percentage of compounds (12b, 12d, 12e, 12i, 12j and 12k) at 10 µm dose in the full pa...
<p>The number of compounds found to demonstrate inhibition at 10μM overall and with respect to the t...
<p>Values are means of two to five experiments ± standard deviation.</p>†<p>ND, not determined.</p><...
<p>Open boxes with – indicate that compounds failed the Primary Screen criterion of >50% inhibition ...
<p>Bars indicate the difference between the percentage inhibition observed using 0.11 mM GAL as subs...
<p>The Inhibition of ligand binding to neurotransmitter receptors by <i>l</i>-THBr.</p
<p>Inhibition of PARP activity by selected seven compounds whose tested concentrations were 0.1 µM, ...
Overactivity of α5 subunit-containing GABAA (α5GABAA) receptors contributes to cognitive deficits in...
a<p>Ki values are taken from three experiments, expressed as means ±SEM.</p>b<p>The Ki values were n...
<p>(A) Effect of antagonists (100 µM) on 5-HT (100 nM) mediated receptor activation. Receptor activa...
Our objective was to characterize the neurotoxic actions of systemically administered domoic acid on...
<p>Inhibition [%] of complexes 1 and 2 [dose level of 25.0 μM] against human tumor cells.</p
Percent cell inhibition of DXH, EpiDXH and DNR against (a) H-1299 and (b) H-157 cell lines.</p
N-Methyl-D-aspartate (NMDA) receptor ligands regulate the bind-ing of uncompetitive antagonists in m...
<p>EGF, epidermal growth factor; HMG CoA, 3-hydroxy-3-methyl-glutaryl coenzyme A. Negative value of ...
<p>Inhibition percentage of compounds (12b, 12d, 12e, 12i, 12j and 12k) at 10 µm dose in the full pa...
<p>The number of compounds found to demonstrate inhibition at 10μM overall and with respect to the t...
<p>Values are means of two to five experiments ± standard deviation.</p>†<p>ND, not determined.</p><...
<p>Open boxes with – indicate that compounds failed the Primary Screen criterion of >50% inhibition ...
<p>Bars indicate the difference between the percentage inhibition observed using 0.11 mM GAL as subs...
<p>The Inhibition of ligand binding to neurotransmitter receptors by <i>l</i>-THBr.</p
<p>Inhibition of PARP activity by selected seven compounds whose tested concentrations were 0.1 µM, ...
Overactivity of α5 subunit-containing GABAA (α5GABAA) receptors contributes to cognitive deficits in...
a<p>Ki values are taken from three experiments, expressed as means ±SEM.</p>b<p>The Ki values were n...
<p>(A) Effect of antagonists (100 µM) on 5-HT (100 nM) mediated receptor activation. Receptor activa...
Our objective was to characterize the neurotoxic actions of systemically administered domoic acid on...
<p>Inhibition [%] of complexes 1 and 2 [dose level of 25.0 μM] against human tumor cells.</p
Percent cell inhibition of DXH, EpiDXH and DNR against (a) H-1299 and (b) H-157 cell lines.</p
N-Methyl-D-aspartate (NMDA) receptor ligands regulate the bind-ing of uncompetitive antagonists in m...