First-pass perfusion MR images and time intensity curves of P792.

<p>A. Gd-DTPA delayed enhancement image. B. Corresponding TTC staining picture. C. Time intensity curves obtained from the first passage of P792. D. Corresponding P792 first-pass perfusion images. The chronic anterior-lateral wall infarction was hyper-enhanced in Gd-DTPA delayed enhanced image (Arrowhead, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0121326#pone.0121326.g004" target="_blank">Fig. 4A</a>) and was confirmed in TTC staining picture (Arrowhead, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0121326#pone.0121326.g004" target="_blank">Fig. 4B</a>). The bolus of P792 caused a rapid and equivalent signal increase in chronic infarction and normal myocardium (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0121326#pone.0121326.g004" target="_blank">Fig. 4C</a>). The chronic infarction did not show perfusion abnormalities with fewer enhancements relative to normal myocardium (Arrowheads, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0121326#pone.0121326.g004" target="_blank">Fig. 4D</a>).