Radiological analysis and callus formation (Cohorts 1, 2, and 7).

<p>Only infectious Cohorts 2 and 7 are shown for comparison while Cohort 1 is included as a non-infection comparator. The presence of a distinct boney callus in Cohorts 1 and an incomplete bridging callus in Cohort 7 are indicative of bone healing. Although soft tissue inflammation cannot be quantitatively assessed, there appeared to be little or no soft tissue inflammation in Cohort 7 compared to Cohort 1, indicating a relatively normal bone healing response. Cohort 2 shows pronounced signs of infection as the device is displaced (indicated by a red arrow).