Bronchodilator responses in lung slices from mice treated with PBS or LPS for four days.

<p>Lung slices were prepared from PBS- (open bars) or LPS- (closed bars) treated mice. Airways were pre-contracted with 5HT (300 nM) prior to addition of ISO (10 μM, green) or RGZ (100 μM, blue). Upper panel: representative trace of the protocol of pre-contraction and relaxation to each dilator agent. Lower panel: grouped data of the bronchodilator responses are expressed as a % relaxation of the sub-maximal pre-contraction (mean ± S.E.M) for n = 3–4 where n represents one slice per mouse.