The effect of <i>in vitro</i> LPS treatment on potency and maximum contraction to MCh and 5HT.

<p>Slices from naive mice were incubated in the absence or presence of LPS (10 μg/ml, 2–48 h). pEC₅₀ and maxima were obtained from fitted individual concentration-response curves. Maximum represented as a % reduction in airway lumen area. n = 3–4 per group.</p><p>*P&lt;0.05 <i>cf</i> media 18 h.</p><p>The effect of <i>in vitro</i> LPS treatment on potency and maximum contraction to MCh and 5HT.