Impaired virulence of pneumococcal strains defective in galactose catabolic pathways following intranasal infection.

<p>(<i>A</i>) Survival time of mice after infection with approximately 1 X 10⁶ CFU pneumococci. Symbols show the times mice became severely lethargic. The horizontal bars mark the median times to the severely lethargic state. (<i>B</i>) Growth of bacteria in the blood. Each point is the mean of data from ten mice except for D39, which represents 20 mice. Error bars show the standard error of the mean. Symbols: * <i>p</i><0.05; ** <i>p</i><0.01; *** <i>p</i><0.001.