<i>In vivo</i> effect of sAPRIL-BP on proliferation and apoptosis in xenograft tumors.

<p>Paraffin embedded tumor tissues were used for morphological analysis with H&E staining (A), proliferation analysis with Ki67 staining (B), and apoptosis analysis with cleaved caspase-3 (cle-casp-3) staining (C). Representative pictures of the tumors from each group are shown (magnification 200×). The proliferation index (D) and apoptosis index (E) were calculated and normalized to the control (Con) group. *<i>p</i> <0.05 compared to control. #<i>p</i> <0.05 compared to 20 mg/kg group.