Homochiral Metal–Organic Framework with Intrinsic Chiral Topology and Helical Channels

Presented here is an unusual microporous metal–organic framework (<b>FIR-30</b>) integrating helical channels, intrinsical chirality, and permanent porosity. The structure of <b>FIR-30</b> containing three types of cages has two interpenetrating helical channel systems with opposite handedness, which can be considered a surface with the same topology as gyroid, and the generation of chirality is related with the intrinsically chiral topology of <b>FIR-30</b>. The results provide new insight toward the construction of chiral MOFs with helical channels