PBMCs from non-pregnant women treated with syncytin-1 prior to infection have a heightened IL-10 response.

<p>PBMCs were infected with H1N1 MOI 0.1 for 48hrs with and without syncytin-1 (1 μM). Levels of IL-10 were measured in culture supernatants by cytometric bead array. Non-pregnant PBMC demonstrated a heightened IL-10 response when exposed to H1N1pdm09 infection and syncytin-1. NPNV = Non-pregnant and non-vaccinated n = 10, PNV = Pregnant and non-vaccinated n = 12. ANOVA (Holm-Sidak) **** <i>P</i> < 0.0001, *** <i>P</i> < 0.001, **<i>P</i> < 0.01.