<p>A-C. Confocal transverse sections of the zebrafish proximal pronephric tubule of 72 hpf wild-type (WT) and <i>ocrl<sup>-/-</sup></i> mutant embryos labelled with antibodies to EEA1 or endofin (A), or to GFP (B and C) to detect expressed GFP-Rab11 (B) or GFP-Rab7 (C). White dashed lines indicate the outline of pronephric tubules. Scale bars represent 10 μm.</p
Midline convergence of organ primordia is an important mechanism for shaping the vertebrate body-pla...
The nephron, the basic functional unit of the kidney, is composed of a glomerulus (blood filter) and...
Nephrons possess a segmental organization where each segment is specialized for the secretion and re...
<p>A. Block face scanning electron microscopy (SEM) images of transverse sections through the zebraf...
<p>A. Confocal images of pronephric cilia, detected using anti-acetylated tubulin antibody, in wild-...
<p>A. Confocal images of wild-type (WT), <i>ocrl<sup>-/-</sup></i> mutant, control morphant or OCRL1...
<p>(A–C,E,F) Red: anti-BrdU staining, Green: anti-GFP staining. BrdU incorporation was measured for ...
<div><p>Lowe syndrome and Dent-2 disease are caused by mutation of the inositol 5-phosphatase OCRL1....
<p>A. RT-PCR detection of PIP5Kαb and eIF1α in wild-type and <i>ocrl<sup>-/-</sup></i> embryos at th...
<p>A. Transverse confocal images of the proximal pronephric region of wild-type (WT) and <i>ocrl<sup...
AbstractPodocytes are specialized cells of the kidney that form the blood filtration barrier in the ...
The zebrafish pronephric kidney provides a simplified model of nephron development and epithelial ce...
<p>(<b>A</b>) Diagram of the exon and intron organization of zebrafish <i>stx16</i>. Thick red lines...
Background: von Hippel-Lindau (VHL) disease is characterized by the development of benign and malign...
Additional file 5: Figure S5. Role of RA and Efhc2 in pronephros segmentation. Wild-type embryos or ...
Midline convergence of organ primordia is an important mechanism for shaping the vertebrate body-pla...
The nephron, the basic functional unit of the kidney, is composed of a glomerulus (blood filter) and...
Nephrons possess a segmental organization where each segment is specialized for the secretion and re...
<p>A. Block face scanning electron microscopy (SEM) images of transverse sections through the zebraf...
<p>A. Confocal images of pronephric cilia, detected using anti-acetylated tubulin antibody, in wild-...
<p>A. Confocal images of wild-type (WT), <i>ocrl<sup>-/-</sup></i> mutant, control morphant or OCRL1...
<p>(A–C,E,F) Red: anti-BrdU staining, Green: anti-GFP staining. BrdU incorporation was measured for ...
<div><p>Lowe syndrome and Dent-2 disease are caused by mutation of the inositol 5-phosphatase OCRL1....
<p>A. RT-PCR detection of PIP5Kαb and eIF1α in wild-type and <i>ocrl<sup>-/-</sup></i> embryos at th...
<p>A. Transverse confocal images of the proximal pronephric region of wild-type (WT) and <i>ocrl<sup...
AbstractPodocytes are specialized cells of the kidney that form the blood filtration barrier in the ...
The zebrafish pronephric kidney provides a simplified model of nephron development and epithelial ce...
<p>(<b>A</b>) Diagram of the exon and intron organization of zebrafish <i>stx16</i>. Thick red lines...
Background: von Hippel-Lindau (VHL) disease is characterized by the development of benign and malign...
Additional file 5: Figure S5. Role of RA and Efhc2 in pronephros segmentation. Wild-type embryos or ...
Midline convergence of organ primordia is an important mechanism for shaping the vertebrate body-pla...
The nephron, the basic functional unit of the kidney, is composed of a glomerulus (blood filter) and...
Nephrons possess a segmental organization where each segment is specialized for the secretion and re...