BuChE activity, but not AChE activity, correlates with levels of C3 and NFL.

<p>BuChE activity was not different between MS patients and controls at the group level, however, with a large spread within groups (A). A highly significant correlation between BuChE activity and C3 levels is evident (B). Also, BuChE activity correlated with levels of NFL (C) and demonstrates a close to significant trend for correlation to EDSS (D). Interestingly, AChE activity differs between MS patients and controls (E), but lacks correlation to C3 at the individual level (F). *p = < 0.05; ** = p < 0.01; *** = p < 0.001.