Size distribution of flat ACF and tumors in the colon of A/J Min/+ mice.

<p>A) mice fed four different diets, (△) Control; (<b>●</b>) Hemin; (<b>◇</b>) Hemin+Nitrite; (<b>■</b>) Nitrite, and B) mice fed diets with or without hemin, (<b>●</b>) Hemin⁺; (○) Hemin^-. The smallest size class contained lesions with 1–4 crypts. One crypt had an area of 0.002mm².In the colon, lesions are considered tumors if they contain more than 30 crypts/lesion (approximately 0.4mm²).