Behavioral summary of <i>L3mbtl1</i> null mutant and control mice at baseline.

<p>(<b>A</b>) General activity, (a) body weight and (b) locomotion. (<b>B</b>) Depression, (a) forced swim and (b) tail suspension (N = 25-28/genotype and test). (<b>C</b>) Anxiety, (a) elevated plus maze, (b) light-dark box, (c) open-field test (N = 17–21 genotype/test). (<b>D</b>) cognition, assessed by contextual fear conditioning (N = 12 <i>L3mbtl1-/-</i> and N = 17 <i>L3mbtl1+/+</i>). Animals used for general activity and depression assays were from a different batch than the animals used for anxiety assays. A third batch of animals was used for the fear conditioning assays. All animals are kept under baseline conditions (group housing). All data are shown as mean ± S.E.M., * P <0.05; independent-samples t test and, for fear conditioning assay, repeated measures ANOVA.