Behavior in an open field was tested in male and female Nurr1 +/+ and +/- mice.

<p>Total distance traveled (A., B.) and time in the center (C., D.) are shown based on genotype (A., C.) and genotype and sex (B., D.). The +/- mice were significantly more active than the +/+ mice as indicated by distance traveled, however, there was no significant interaction between genotype and sex (B.). Additionally, the +/- mice spent significantly more time in the center of the chamber than the +/+ mice (C.), which also showed no interaction between genotype and sex (D.). *significant difference based on ANOVA with Fischer’s post hoc comparison. n = 18 female +/+; 19 female +/-; 29 male +/+; 18 male +/-.