<p>4–1 is a chimera, 4–3 is a homozygote, and 4–14, 4–19, and 6–5 are heterozygotes. The sequence between two arrows is the spacer cut by TALEN. The scissors indicate three-base deletions and the asterisk indicates the targeted base substitution C<sup>317</sup>-T.</p
Sequencing chromatograms from the affected individual IV-1 and parent II-1. Arrows mark two differen...
(Upper panel) Sequencing chromatograms from the affected individual II-1 and parent I-1 from the fam...
<div><p>(A) Sequence of unique PCR product generated with specific <i>CFH</i> (forward) and <i>CFHL1...
<p>The genotype and detailed sequence variation of some typical mutants from chimera, homozygote and...
<p>(A) Each arrow indicates the position of the nucleotide variant that results in the substitution ...
(Upper panel) Sequencing chromatograms from the affected individual IV-1 and the parent III-1 showin...
(Upper panel) Sequencing chromatograms from the affected individual II-2 and the parent I-1 from fam...
(Upper panel) Sequencing chromatograms from the affected individual V-1 and parent IV-1 from family-...
(Upper panel) Sequencing chromatogram of the affected individual IV-5 from family-128. Arrow marks t...
<p>Green letters designate target sequences of TALENs. Red dashes and blue letters indicate deleted ...
(Upper panel) Sequencing chromatograms from the affected individual II-2 and parent I-1 from family-...
(Upper panel) Sequencing chromatogram from the affected individual II-2 from family-123. Arrow marks...
<p>(A) Double peaks labeled with an arrow represented the heterozygous genotype TC (AG). (B) Single ...
<p>(A) Sequencing data of amplified regions. Numbers on upper right corner indicate the highest cove...
<p>The letters on the top are the expected DNA sequences. The downward arrows and the upward arrows ...
Sequencing chromatograms from the affected individual IV-1 and parent II-1. Arrows mark two differen...
(Upper panel) Sequencing chromatograms from the affected individual II-1 and parent I-1 from the fam...
<div><p>(A) Sequence of unique PCR product generated with specific <i>CFH</i> (forward) and <i>CFHL1...
<p>The genotype and detailed sequence variation of some typical mutants from chimera, homozygote and...
<p>(A) Each arrow indicates the position of the nucleotide variant that results in the substitution ...
(Upper panel) Sequencing chromatograms from the affected individual IV-1 and the parent III-1 showin...
(Upper panel) Sequencing chromatograms from the affected individual II-2 and the parent I-1 from fam...
(Upper panel) Sequencing chromatograms from the affected individual V-1 and parent IV-1 from family-...
(Upper panel) Sequencing chromatogram of the affected individual IV-5 from family-128. Arrow marks t...
<p>Green letters designate target sequences of TALENs. Red dashes and blue letters indicate deleted ...
(Upper panel) Sequencing chromatograms from the affected individual II-2 and parent I-1 from family-...
(Upper panel) Sequencing chromatogram from the affected individual II-2 from family-123. Arrow marks...
<p>(A) Double peaks labeled with an arrow represented the heterozygous genotype TC (AG). (B) Single ...
<p>(A) Sequencing data of amplified regions. Numbers on upper right corner indicate the highest cove...
<p>The letters on the top are the expected DNA sequences. The downward arrows and the upward arrows ...
Sequencing chromatograms from the affected individual IV-1 and parent II-1. Arrows mark two differen...
(Upper panel) Sequencing chromatograms from the affected individual II-1 and parent I-1 from the fam...
<div><p>(A) Sequence of unique PCR product generated with specific <i>CFH</i> (forward) and <i>CFHL1...