Macrophages and microglia and the suggested roles of sCD163, CXCL13, NEO, NfL, OPN, and IgG in MS pathology.
- Morten Stilund (571168)
- Mikkel Carstensen Gjelstrup (720659)
- Thor Petersen (136208)
- Holger Jon Møller (38785)
- Peter Vestergaard Rasmussen (571170)
- Tove Christensen (136206)
Publication date
April 2015
DOIAbstract
<p>Fig 1 shows the biomarkers sCD163, CXCL13, NEO, NfL and OPN and their relation to monocyte activation, macrophage migration, and interactions with macrophages/microglia in active (acute/chronic) MS lesions. Biomarker characteristics are listed below: Abbreviations: sCD163 (soluble CD163), mCD163 (membrane bound CD163), NEO (neopterin), NfL (neurofilament light polypeptide), OPN (osteopontin), Th-cells (T helper cells), MS (multiple sclerosis), CSF (cerebrospinal fluid), EC (epithelial cell), Ag (antigen), SC (Schwann cell), OND (other neurological disease), ROS (reactive oxygen species).</p
Add to ORKG