Glucose disposal rates in lean and obese volunteers before and after surgery.

<p>A comparison of glucose concentration (panel A), insulin concentrations (panel B) and glucose disposal (panel C), between lean (filled triangles) and obese volunteers before (open circles; pre-op) and after (filled squares; post-op) surgery, measured during a 10 hour hyperinsulinaemic euglycaemic clamp. Insulin infusion rates of 0, 0.5, 1, 2 and 5 mU kg-1 min-1 were used. Data points represent the mean ± SEM where * represents P<0.05 determined by unpaired t tests, between lean and pre-op obese volunteers; + represents P<0.05 determined by unpaired t tests between lean and post-op obese volunteers; # represents P<0.05 determined by paired t tests between pre-op and post-op obese volunteers. Glucose disposal rates were different between lean and obese volunteers (MANCOVA, P<0.001), and in obese volunteers before and after surgery (MANCOVA, P<0.05).