<div><p>Atrial septal defect (ASD) is the third most frequent type of congenital heart anomaly, featuring shunting of blood between the two atria. Gene-environment interaction remains to be an acknowledged cause for ASD occurrence. A recent European genome-wide association study (GWAS) of congenital heart disease (CHD) identified 3 susceptibility SNPs at chromosome 4p16 associated with ASD: <i>rs870142</i>, <i>rs16835979</i> and <i>rs6824295</i>. A Chinese-GWAS of CHD conducted in the corresponding period did not reveal the 3 susceptibility SNPs, but reported 2 different risk SNPs: <i>rs2474937</i> and <i>rs1531070</i>. Therefore, we aimed to investigate the associations between the 3 European GWAS-identified susceptibility SNPs and ASD ris...
Background: Congenital heart defects (CHD) is the most common cause of death from a congenital struc...
Background: Congenital heart defects (CHD) is the most common cause of death from a congenital struc...
A recent genome-wide association study identified a haplotype block on chromosome 4q25 associated wi...
Atrial septal defect (ASD) is the third most frequent type of congenital heart anomaly, featuring sh...
We carried out a genome-wide association study (GWAS) of congenital heart disease (CHD). Our discove...
We carried out a genome-wide association study (GWAS) of congenital heart disease (CHD). Our discove...
We carried out a genome-wide association study (GWAS) of congenital heart disease (CHD). Our discove...
<div><p>A recent genome-wide association study (GWAS) has identified a new subset of susceptibility ...
A recent genome-wide association study (GWAS) has identified a new subset of susceptibility loci of ...
A recent genome-wide association study (GWAS) has identified a new subset of susceptibility loci of ...
Development of the cardiac atrial septum involves complex morphogenetic processes including programm...
Background: In a recent nationwide cohort study, we have discovered that patients living with an atr...
Congenital heart defects (CHD) are the most common developmental errors in humans, affecting 8 out o...
Atrial fibrillation is a highly prevalent arrhythmia and a major risk factor for stroke, heart failu...
Genetic factors undoubtedly affect the development of congenital heart disease (CHD) but still remai...
Background: Congenital heart defects (CHD) is the most common cause of death from a congenital struc...
Background: Congenital heart defects (CHD) is the most common cause of death from a congenital struc...
A recent genome-wide association study identified a haplotype block on chromosome 4q25 associated wi...
Atrial septal defect (ASD) is the third most frequent type of congenital heart anomaly, featuring sh...
We carried out a genome-wide association study (GWAS) of congenital heart disease (CHD). Our discove...
We carried out a genome-wide association study (GWAS) of congenital heart disease (CHD). Our discove...
We carried out a genome-wide association study (GWAS) of congenital heart disease (CHD). Our discove...
<div><p>A recent genome-wide association study (GWAS) has identified a new subset of susceptibility ...
A recent genome-wide association study (GWAS) has identified a new subset of susceptibility loci of ...
A recent genome-wide association study (GWAS) has identified a new subset of susceptibility loci of ...
Development of the cardiac atrial septum involves complex morphogenetic processes including programm...
Background: In a recent nationwide cohort study, we have discovered that patients living with an atr...
Congenital heart defects (CHD) are the most common developmental errors in humans, affecting 8 out o...
Atrial fibrillation is a highly prevalent arrhythmia and a major risk factor for stroke, heart failu...
Genetic factors undoubtedly affect the development of congenital heart disease (CHD) but still remai...
Background: Congenital heart defects (CHD) is the most common cause of death from a congenital struc...
Background: Congenital heart defects (CHD) is the most common cause of death from a congenital struc...
A recent genome-wide association study identified a haplotype block on chromosome 4q25 associated wi...