Morphological changes in the spleen of dogs naturally infected by <i>Leishmania infantum</i>.

<p>(A) Organized splenic white pulp compartments with well-formed follicle; (B) Moderately disorganized splenic white pulp when the white pulp was evident, however, its regions were poorly individualized or indistinct; (C) Disorganized splenic white pulp without compartment distinction; (D, E and F) Intracelullar amastigotes (arrows). HE, Scale bar 20 μm (A, B and C); 10 μm (D, E and F). WP—white pulp; RP—red pulp; BCA—B cell area; PALS—periarterial lymphoid sheat; CA—central artery.