Bam32^-/- mice are susceptible to experimental <i>Trypanosoma congolense</i> infection.

<p>Groups of Bam32^-/- and WT C57BL/6 mice were infected intraperitoneally with 10³<i>T</i>. <i>congolense</i>, clone TC13. Daily parasitemia (A) was estimated by direct counting of tail blood smears in at least 10 fields at 400X magnification. Infected mice were followed over time and the percentage survival (B) was recorded. At indicated times, infected mice were sacrificed and the liver (C) and spleen (D) weights were determined. In addition, serum levels of ALT (E) and AST (F) were determined. Results are representative of 3 (A and B) and 2 (C-F) different experiments (n = 3–5 mice per experiment) with similar outcome. ns, not significant. *, p < 0.05; **, p < 0.01