<p>(A) All GFP positive cells within the GL261 tumor are clearly positive for PDGFR-β. (B) Out of all PDGFR-β positive cells within the tumor, 57 ± 6.6% are host-derived GFP positive cells (n = 3, mean ± SEM). (C) A proportion of the cells are positive for the activation marker NG2. The majority of the GFP positive cells lack expression of the mesenchymal stromal cell marker CD13. (D) GFP positive cell at the tumor border expressing CD13. (E) The majority of the cells weakly express the pericyte marker α-SMA. Scale bar is 500 μm in the low magnification images and 20 μm in the high magnification images.</p
<p><b>A</b>) The total fraction of pxl. positive for NG2 or α-SMA were quantitated. <b>B</b>) The am...
<p>Expression of MAP2 (n = 5), GFAP (n = 8), cytokeratin (n = 9), and CD34 (n = 5), which identify p...
<p>(<b>A</b>) Immunofluorescent staining followed by confocal microscopy showing examples of represe...
<p>(A) A subset of the GFP positive cells within GL261 tumors express the proliferation marker Ki67,...
<p>(A) GFP positive cells (arrows) are attracted more numerous within the penumbra zone around GLUT1...
<p>(A) Overview image of GL261 tumor expressing high levels of laminin, scale bar is 1000 μm. (B) Hi...
<p>Consecutive sections of benign prostate tissue (A, B) and tumor tissue (C, D, E) stained for PDGF...
<p>(<b>A</b>) Representative FACS analyses of the different cell surface markers expression in unsor...
<p>A. Left panel: representative confocal images of PDGFRA immunohistochemistry staining in glioma s...
<p>(A) Low magnification photomicrograph of a normal rgs5<sup>GFP/+</sup> mouse brain, scale bar is ...
<p>Sections of Oct4GFP+ or NanogGFP+ MT/ret, MMTV-PyMT and MMTV-Neu tumors were stained with an anti...
<p><b>A</b>) Tumor stained with FGFR2 antibody. Patient 1 demonstrates moderate cytoplasmic positivi...
<p>A: Expression of PDGF-C in human samples of gliomas. 27 samples of Grade IV glioma (Tissue Microa...
<p>A) Immunofluorescence for PDGF-GFP (green) and GFAP (red) in a PDGF-GFP-driven glioma shows expre...
Solid tumors contain non-transformed cells of critical importance for disease progression. These cel...
<p><b>A</b>) The total fraction of pxl. positive for NG2 or α-SMA were quantitated. <b>B</b>) The am...
<p>Expression of MAP2 (n = 5), GFAP (n = 8), cytokeratin (n = 9), and CD34 (n = 5), which identify p...
<p>(<b>A</b>) Immunofluorescent staining followed by confocal microscopy showing examples of represe...
<p>(A) A subset of the GFP positive cells within GL261 tumors express the proliferation marker Ki67,...
<p>(A) GFP positive cells (arrows) are attracted more numerous within the penumbra zone around GLUT1...
<p>(A) Overview image of GL261 tumor expressing high levels of laminin, scale bar is 1000 μm. (B) Hi...
<p>Consecutive sections of benign prostate tissue (A, B) and tumor tissue (C, D, E) stained for PDGF...
<p>(<b>A</b>) Representative FACS analyses of the different cell surface markers expression in unsor...
<p>A. Left panel: representative confocal images of PDGFRA immunohistochemistry staining in glioma s...
<p>(A) Low magnification photomicrograph of a normal rgs5<sup>GFP/+</sup> mouse brain, scale bar is ...
<p>Sections of Oct4GFP+ or NanogGFP+ MT/ret, MMTV-PyMT and MMTV-Neu tumors were stained with an anti...
<p><b>A</b>) Tumor stained with FGFR2 antibody. Patient 1 demonstrates moderate cytoplasmic positivi...
<p>A: Expression of PDGF-C in human samples of gliomas. 27 samples of Grade IV glioma (Tissue Microa...
<p>A) Immunofluorescence for PDGF-GFP (green) and GFAP (red) in a PDGF-GFP-driven glioma shows expre...
Solid tumors contain non-transformed cells of critical importance for disease progression. These cel...
<p><b>A</b>) The total fraction of pxl. positive for NG2 or α-SMA were quantitated. <b>B</b>) The am...
<p>Expression of MAP2 (n = 5), GFAP (n = 8), cytokeratin (n = 9), and CD34 (n = 5), which identify p...
<p>(<b>A</b>) Immunofluorescent staining followed by confocal microscopy showing examples of represe...